Those who have difficulty with drunk effects (blurred screen makes some get a headache) may want to bring Pot of Wake-up Juice or Hair of the Dog along. The quest from Sam, which is easier to do immediately following this quest, is one of the worst for the drunk effect blur.
You can also just lose a duel against a other player -- equipment takes no damage -- and you are sober right away.
Go behind the curtain at Loc ( 329, -21, 145 ) /waypoint 329, -21, 145 and take the stairs down. Then click on the trap door at Loc ( 339, -27, 144 ) /waypoint 339, -27, 144 to zone into the Serilian Bar.
Speak to Sam the ratonga bartender for the quest update.
Sam will offer you the next quest at this point also.